Biotin-azide
CAS:908007-17-0
品牌:MedChemExpress (MCE)
存储条件:Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
生物活性:Biotin-azide (N-(3-Azidopropyl)biotinamide) 是一种带有末端叠氮基的生物素。通过 Click Chemistry[1][2],生物素-叠氮化物可用于制备各种生物素化偶联物。
体外:使用生物素-叠氮化物探针进行点击化学功能化后交联,可以从酵母细胞中分离转录蛋白复合物[3]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献:
[1]. Bruckman MA, et al. Tobacco mosaic virus-based protein nanoparticles and nanorods for chemotherapy delivery targeting breast cancer. J Control Release. 2016;231:103‐113.
[2]. Kim HY, et al. An azido-biotin reagent for use in the isolation of protein adducts of lipid-derived electrophiles by streptavidin catch and photorelease. Mol Cell Proteomics. 2009;8(9):2080‐2089.
[3]. Joiner CM, et al. A Bifunctional Amino Acid Enables Both Covalent Chemical Capture and Isolation of in Vivo Protein-Protein Interactions. Chembiochem. 2017 Jan 17;18(2):181-184.
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