参考详情:https://www.medchemexpress.cn/Spermine.html
中文名:精胺
CAS:71-44-3
品牌:MedChemExpress (MCE)
存储条件:4°C, sealed storage, away from moisture and light
生物活性: Spermine (NSC 268508) 直接充当自由基清除剂,保护 DNA 免受自由基攻击。精胺具有抗病毒作用。
体外:生理相关浓度的精胺 (NSC 268508) 可抑制 ROS 诱导的 DNA 损伤,在 1 至 2 mM 时观察到最大抑制作用。这些浓度完全在精胺生理浓度的估计范围内[1]。
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研究领域:Metabolic Enzyme/Protease|Anti-infection
作用靶点:Endogenous Metabolite|Influenza Virus
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
参考文献:
[1]. Ha HC, et al. The natural polyamine spermine functions directly as a free radical scavenger. Proc Natl Acad Sci U S A. 1998 Sep 15;95(19):11140-5.
[2]. Mounce BC, et al. Polyamines and Their Role in Virus Infection. Microbiol Mol Biol Rev. 2017 Sep 13;81(4). pii: e00029-17.
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