CAS:3055-98-9
品牌:MedChemExpress (MCE)
存储条件:Pure form: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
生物活性:八甘醇单十二烷基醚 (C12E8) 是一种非离子型去污剂,可用于膜蛋白提取。八乙二醇单十二烷基醚可溶解完整流感病毒[1][2]的病毒膜。
体外:八乙二醇单十二烷基醚 (C12E8) 已显示可溶解完整流感病毒的病毒膜。病毒膜增溶的机制是基于 C12E8 分子在膜外的积累,直至形成胶束,从而导致膜成分的提取[1]。
参考详情:https://www.medchemexpress.com/golimumab.html
参考文献:
[1]. Véronique Nardello-Rataj, et al. Aqueous solutions of didecyldimethylammonium chloride and octaethylene glycol monododecyl ether: Toward synergistic formulations against enveloped viruses. Int J Pharm. 2016 Sep 10;511(1):550-559.
[2]. C Carnero Ruiz, et al. Characterization of mixed non-ionic surfactants n-octyl-β-D-thioglucoside and octaethylene-glycol monododecyl ether: micellization and microstructure. J Colloid Interface Sci. 2011 Sep 1;361(1):178-85.
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