如何在python中删除wav文件中的静默期？

import wave
import audioop

wav_file = wave.open('file.wav', 'rb')
sample_width = wav_file.getsampwidth()
frame_rate = wav_file.getframerate()

def is_silence(data, threshold):
    rms = audioop.rms(data, sample_width)
    return rms < threshold

def remove_silence(input_file, output_file, threshold):
    input_wav = wave.open(input_file, 'rb')
    output_wav = wave.open(output_file, 'wb')
    output_wav.setparams(input_wav.getparams())

    frames = input_wav.readframes(input_wav.getnframes())
    while frames:
        if not is_silence(frames, threshold):
            output_wav.writeframes(frames)
        frames = input_wav.readframes(input_wav.getnframes())

    input_wav.close()
    output_wav.close()

remove_silence('input.wav', 'output.wav', threshold)