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信令（Signaling）

我们把这些消息称为信令（Signaling）。 - 信令分类 - 信令主要有以下几种分类方式：按信令的功能分：线路信令：具有监视功能，用来监视主被叫的摘、挂机状态及设备忙闲。

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ble4.2 L2CAP层信令通道包详解（SIGNALING PACKET FORMATS）

可以看出BLE主要使用0x0004、0x0005、0x0006三个信道；0x0004用于ATT协议，0x0005用于L2CAP信令，0x0006用于安全管理。

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Java线程通信（Thread Signaling）利用共享对象实现通信忙等（busy waiting）wait(), notify() and notifyAll()信号丢失（Missed Sign

线程通信的目的就是让线程间具有互相发送信号通信的能力。而且，线程通信可以实现，一个线程可以等待来自其他线程的信号。举个例子，一个线程B可能正在等待来自线程A...

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手画综合信号通路（部分）

自噬 ○1 mTOR Signaling ○2 AMPK Signaling ○3PI3K/Akt Signaling ○4 p53 Signaling ○5Hedgehog signaling 自噬...生物氧化 ○1PKA Signaling ○2PIK3/AKT Signaling ○3AMPK Signaling生物氧化 ?...脂类代谢 ○1 AMPK Signaling ○2 PKA Signaling ○3 PPAR Signaling ○4 Dopamine Receptor Signaling ○5Aryl Hydrocarbon...Receptor Signaling ○6Sphingosine-1-phosphate Signaling ○7Serotonin Receptor Signaling脂类代谢

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CellChat细胞通讯（二）可视化篇

This hierarchical plot consist of two components: the left portion shows autocrine and paracrine signaling...to fibroblast and the right portion shows signaling to immune cells vertex.receiver = c(1,2,3,4) #...netVisual_aggregate(cellchat, signaling = pathways.show, vertex.receiver = vertex.receiver, layout =...= pathways.show, layout = "circle") netVisual_aggregate(cellchat, signaling = pathways.show, layout...pathways (where each sector in the chord diagram is a ligand, receptor or signaling pathway.)

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如何在kubernetes中实现分布式可扩展的WebSocket服务架构

WebRTC signaling 是WebRTC协议的前置步骤，它依赖signaling server在需要建立WebRTC连接的客户端之间转发协商协议。...客户端和signaling server之间的连接通常使用WebSockets。...每个signaling实例需要了解系统中的其他实例，这可以通过kubernetes中的Headless Service关联signaling deployment，然后调用Kubernetes Endpoints...实现步骤如下：通过kubernetes API来发现signaling实例，并实现rendezvous哈希逻辑。...当返回的实例与当前客户端注册的不一致，则负载均衡器只会断开与该客户端相关的负载均衡器-signaling 之间的WebSocket，并重新建立一条到正确的signaling实例的负载均衡器-signaling

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本地 k8s 部署

app: signaling-0 replicas: 1 template: metadata: labels: app: signaling-...0 spec: containers: - name: signaling image: code.com:6543/signaling-server...:latest，监听端口（containerPort）是 21116，将 signaling 这个配置挂载到了 /opt/signaling_server/config/signaling/production.toml...[signaling] data_center = "beijing" service_name = "signaling" signaling_port = 21116.../config/signaling/production.toml。

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Venn网络展示富集分析结果

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多组cellchat细胞通讯批量分析

= i,signaling.name = paste(i,"sigaling"), ,pt.title=10,vertex.receiver...= vertex.receiver, layout = "circle") title(main = paste0(i,' signaling')) print(p) }...= i, title = paste0(i, " signaling pathway", " Contribution of each L-R pair")) print(p) }...role analysis on the aggregated cell-cell communication network from all signaling pathways #> Signaling...= c("MIF")) #> Visualizing differential outgoing and incoming signaling changes from NL to LS #> The

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cellchat-(2)信号通路可视化-上

# 信号通路水平 netVisual_aggregate( cellchat, signaling = "ITGB2", #pathway_name vertex.receiver = c(...1, 3, 5), #指定受体细胞 layout = "hierarchy" #指定输出层次图 ) # 单个配体受体水平 extractEnrichedLR(cellchat, signaling...热图热图也是从整个信号通路水平展示不同细胞间的相互作用： netVisual_heatmap( cellchat, signaling = "ITGB2", color.heatmap ...= "Reds") 图片去掉signaling参数后就是所有细胞间的所有相互作用，类似于第一节中总的相互作用网络图。...计算信号通路中各受体配体对的贡献 netAnalysis_contribution(cellchat, signaling = "ITGB2") 图片这样就能看到不同配体受体对对于该通路的贡献了。

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可视化—KEGG富集图中如何展示特定的通路

#显示特定的通路selected_pathways signaling pathway", "T cell receptor signaling pathway...", "Fc epsilon RI signaling pathway", "PD-L1 expression and PD-1 checkpoint pathway in cancer", "Th1...and Th2 cell differentiation", "IL-17 signaling pathway", "Th17 cell differentiation", "MAPK signaling...pathway", "PI3K-Akt signaling pathway", "Ras signaling pathway")kk_filtered % filter

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CellChat三部曲1：使用CellChat对单个数据集进行细胞间通讯分析

") # use Secreted Signaling # use all CellChatDB for cell-cell communication analysis # CellChatDB.use...df.net signaling = c("WNT", "TGFb"))通过向WNT和TGFb发出信号来调节推断的细胞通信。...# Signaling role analysis on the aggregated cell-cell communication network from all signaling pathways...communication network from all signaling pathways # Signaling role analysis on the cell-cell communication...# Signaling role analysis on the aggregated cell-cell communication network from all signaling pathways

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通过空间行为（optimal transport）推断空间细胞间通讯信号方向(COMMOT)

='mouse', signaling_type='Secreted Signaling', database='CellChat') print(df_cellchat.shape) # filter...1 Tgfb2 Tgfbr1_Tgfbr2 TGFb Secreted Signaling 2 Tgfb3 Tgfbr1_Tgfbr2 TGFb Secreted Signaling...3 Tgfb1 Acvr1b_Tgfbr2 TGFb Secreted Signaling 4 Tgfb1 Acvr1c_Tgfbr2 TGFb Secreted Signaling Now...The signaling results are stored as spot-by-spot matrices in the obsp slots..../adata.h5ad") Determine the spatial direction of a signaling pathway, for example, the PSAP pathway.

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CellChat 三部曲3：具有不同细胞类型成分的多个数据集的细胞通讯比较分析

#> Merge the following slots: 'data.signaling','net', 'netP','meta', 'idents', 'var.features' , 'DB',...to dermal cells and right portion shows signaling to epidermal cells par(mfrow = c(1,2), xpd=TRUE) for...= pathways.show, layout = "circle", edge.weight.max = weight.max[1], edge.width.max = 10, signaling.name...= pathways.show, layout = "chord", signaling.name = paste(pathways.show, names(object.list)[i])) } #...(object.list)[i])) } #> Plot the aggregated cell-cell communication network at the signaling pathway

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🤩 Cellchat | 空间转录组也可以做细胞通讯啦！~（一）（单个数据集篇）

", key = "annotation") # use Secreted Signaling # Only uses the Secreted Signaling from CellChatDB v1...# CellChatDB.use Signaling"), c("CellChatDB v1"))...We do not suggest to use it in this way because CellChatDB v2 includes "Non-protein Signaling" (i.e.,...metabolic and synaptic signaling) that can be only estimated from gene expression data...network, e.g., bigger circle indicates larger incoming signaling par(mfrow=c(1,1)) netVisual_aggregate

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day 10 GSVA和CellChat

assay = "RNA") cellchat@DB Signaling...") cellchat signaling) 开始计算cellchat signaling = pathways.show, color.heatmap = "Reds") #5...计算配体-受体对信号网络的贡献度netAnalysis_contribution(cellchat, signaling = pathways.show) #6 热图展示分析细胞在信号网络中角色：发送者...pathwaysnetAnalysis_signalingRole_network(cellchat, signaling = pathways.show, width = 12, height =

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TSINGSEE青犀视频开发Webrtc的PC Factory三个线程介绍说明

在我们的开发中，需要了解Webrtc的PC Factory拥有三个线程： Signaling_thread_: 这个是所有PC Factory和PC的对外接口，执行都会切换到signaling_thread..._，而PC Observer所有的回调函数也都会在signaling_thread_执行。...webrtc::CreatePeerConnectionFactory( Nullptr/*network_thread_*/, nullptr/*worker_thread_*/, nullptr/*signaling_thread...Factory的第二个参数也没有提供（worker_thread_），就会调用rtc::Thread::Create()来创建并启动耗时相关线程 E、如果PC Factory的第三个参数没有提供，因为signaling_thread..._比较特殊，没有提供时，那么webrtc是不会创建新的线程，而是把当前的线程进行包装一下作为signaling_thread_来用。

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CellChat三部曲2：使用CellChat 对多个数据集细胞通讯进行比较分析

role analysis on the aggregated cell-cell communication network from all signaling pathways #> Signaling...role analysis on the aggregated cell-cell communication network from all signaling pathways patchwork...= pathways.show, layout = "chord", signaling.name = paste(pathways.show, names(object.list)[i])) } #...= pathways.show, group = group.cellType, title.name = paste0(pathways.show, " signaling network - ",...level #> Plot the aggregated cell-cell communication network at the signaling pathway level #> Note:

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docker 镜像制作示例

run 会自动拉取镜像并启动容器： IMAGE_FULL_TAG=镜像仓库/xremote-server:demo CONTAINER_NAME="rustdesk-server-demo" HOST_SIGNALING_PROT...=21116 HOST_RELAY_PROT=21117 CONTAINER_SIGNALING_PORT=21116 CONTAINER_RELAY_PORT21117 IP=127.0.0.1 docker...run -itd --restart=always --net bridge \ --name "${CONTAINER_NAME}" \ -p "${HOST_SIGNALING_PROT...}:${CONTAINER_SIGNALING_PORT}/udp" \ -p "${HOST_SIGNALING_PROT}:${CONTAINER_SIGNALING_PORT}

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从msigdb下载的hallmark基因集里面的基因数量上限是200？？

geneset$gs_name))) Var1 Freq 1 HALLMARK_NOTCH_SIGNALING...34 2 HALLMARK_ANGIOGENESIS 36 3 HALLMARK_HEDGEHOG_SIGNALING...50 7 HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY 58 8 HALLMARK_TGF_BETA_SIGNALING...PATHWAY 215 36 HALLMARK_ESTROGEN_RESPONSE_EARLY 216 37 HALLMARK_IL2_STAT5_SIGNALING...220 41 HALLMARK_KRAS_SIGNALING_UP 220 42 HALLMARK_OXIDATIVE_PHOSPHORYLATION

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信令（Signaling）

ble4.2 L2CAP层信令通道包详解（SIGNALING PACKET FORMATS）

Java线程通信（Thread Signaling）利用共享对象实现通信忙等（busy waiting）wait(), notify() and notifyAll()信号丢失（Missed Sign

手画综合信号通路（部分）

CellChat细胞通讯（二）可视化篇

如何在kubernetes中实现分布式可扩展的WebSocket服务架构

本地 k8s 部署

Venn网络展示富集分析结果

多组cellchat细胞通讯批量分析

cellchat-(2)信号通路可视化-上

可视化—KEGG富集图中如何展示特定的通路

CellChat三部曲1：使用CellChat对单个数据集进行细胞间通讯分析

通过空间行为（optimal transport）推断空间细胞间通讯信号方向(COMMOT)

CellChat 三部曲3：具有不同细胞类型成分的多个数据集的细胞通讯比较分析

🤩 Cellchat | 空间转录组也可以做细胞通讯啦！~（一）（单个数据集篇）

day 10 GSVA和CellChat

TSINGSEE青犀视频开发Webrtc的PC Factory三个线程介绍说明

CellChat三部曲2：使用CellChat 对多个数据集细胞通讯进行比较分析

docker 镜像制作示例

从msigdb下载的hallmark基因集里面的基因数量上限是200？？

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